To give a single instance: not one scholar out of 148, who were at the same time in the London Institution, was the child of parents similarly affected. So again, when a male or female deaf-mute marries a sound person, their children are most rarely affected: in Ireland, out of 203 children thus produced one alone was mute. Even when both parents have been deaf-mutes, as in the case of forty-one marriages in the United States and of six in Ireland, only two deaf and dumb children were produced. Mr. Sedgwick (12/53. 'British and Foreign Med.-Chirurg. Review' July 1861 pages 200-204. Mr. Sedgwick has given such full details on this subject, with ample references, that I need refer to no other authorities), in commenting on this remarkable and fortunate failure in the power of transmission in the direct line, remarks that it may possibly be owing to "excess having reversed the action of some natural law in development." But it is safer in the present state of our knowledge to look at the whole case as simply unintelligible.
Although many congenital monstrosities are inherited, of which examples have already been given, and to which may be added the lately recorded case of the transmission during a century of hare-lip with a cleft-palate in the writer's own family (12/54. Mr. Sproule in 'British Medical Journal' April 18, 1863.) yet other malformations are rarely or never inherited. Of these latter cases, many are probably due to injuries in the womb or egg, and would come under the head of non-inherited injuries or mutilations. With plants, a long catalogue of inherited monstrosities of the most serious and diversified nature could easily be given; and with plants, there is no reason to suppose that monstrosities are caused by direct injuries to the seed or embryo.
With respect to the inheritance of structures mutilated by injuries or altered by disease, it was until lately difficult to come to any definite conclusion. Some mutilations have been practised for a vast number of generations without any inherited result. Godron remarks (12/55. 'De l'Espece' tome 2 1859 page 299.) that different races of man have from time immemorial knocked out their upper incisors, cut off joints of their fingers, made holes of immense size through the lobes of their ears or through their nostrils, tatooed themselves, made deep gashes in various parts of their bodies, and there is no reason to suppose that these mutilations have ever been inherited. (12/56. Nevertheless Mr. Wetherell states, 'Nature' December 1870 page 168, that when he visited fifteen years ago the Sioux Indians, he was informed "by a physician, who has passed much of his time with these tribes, that some times a child was born with these marks. This was confirmed by the U.S. Government Indian Agent.") Adhesions due to inflammation and pits from the small-pox (and formerly many consecutive generations must have been thus pitted) are not inherited. With respect to Jews, I have been assured by three medical men of the Jewish faith that circumcision, which has been practised for so many ages, has produced no inherited effect. Blumenbach, however, asserts (12/57. 'Philosoph. Mag.' volume 4 1799 page 5.) that Jews are often born in Germany in a condition rendering circumcision difficult, so that a name is given them signifying "born circumcised;" and Professor Preyer informs me that this is the case in Bonn, such children being considered the special favourites of Jehovah. I have also heard from Dr. A. Newman, of Guy's Hospital, of the grandson of a circumcised Jew, the father not having been circumcised, in a similar condition. But it is possible that all these cases may be accidental coincidence, for Sir J. Paget has seen five sons of a lady and one son of her sister with adherent prepuces; and one of these boys was affected in a manner "which might be considered like that commonly produced by circumcision;" yet there was no suspicion of Jewish blood in the family of these two sisters. Circumcision is practised by Mahomedans, but at a much later age than by Jews; and Dr.